Chronic Disease

Two existing drugs improve mucus clearance in animal models of cystic fibrosis, indicating a potential pathway to reduce chronic lung infections in humans.

An antibody-based approach for Fanconi anemia replaces traditional toxic conditioning with targeted therapy, allowing safe restoration of blood and immune function without chemotherapy or radiation.

New research suggests that certain genetic variants can decrease the ability of GLP-1 diabetes drugs to regulate blood sugar – a mysterious phenomenon known as GLP-1 resistance.

A calorie-restrictive diet significantly alleviates symptoms of mild-to-moderate Crohn’s disease, offering new guidance for patients.

A key molecule involved in red blood cell production governs whether the immune system attacks or tolerates cells.

The discovery could also open a new path for treating autoimmune diseases and improving organ transplants.

A study led by Stanford Medicine reveals that an unusual type of fat that forms near the intestines in Crohn’s disease can trigger debilitating scars.