Kobilka's work recognized in magazine award

Science magazine has cited the work of Brian Kobilka, MD, professor of molecular and cellular physiology, as a runner-up for the 2007 "Breakthrough of the Year" distinction for identifying the structure of an important cell receptor.

A team headed by Kobilka obtained a high-resolution image of a beta2-adrenergic receptor, one of the G protein-coupled receptors that are prime targets of therapeutic drugs. Such a clear picture of the receptor's structure could lead to more powerful treatments with fewer side effects.

Kobilka published his findings in the Nov. 23 issue of Science. Eight other research advances were named runners up in Science's 2007 "Breakthrough of the Year" award that went to researchers studying human genetic variation. The selections were announced in the Dec. 21 issue of Science.