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Stanford Report, October 1, 2003

Latest round of medical school faculty appointments, promotions announced

By JOYCE THOMAS

Susan I. Brundage, MD, was appointed associate professor of surgery (general surgery). Her basic research, funded in part by an American Association for the Surgery of Trauma grant, has focused on the underlying mechanisms of the amplification of the pro-inflammatory response following shock. She was the principal investigator of a single-center comparative trial of methods of treating gastrointestinal wounds in trauma patients. The study led to a multi-center trial sponsored by the Western Trauma Association.

She received her undergraduate degree from Stanford in 1986 and her medical degree from the University of Iowa in 1990. She completed a residency at George Washington University and a fellowship in trauma and surgical critical care at Harborview Hospital, University of Washington. In 1998 she joined the faculty at Baylor College of Medicine and served as director of the emergency department surgical service at Ben Taub Hospital.

Leland Hanowell, MD, was appointed associate professor of anesthesia. He is an expert in the anesthetic management of patients with trauma. His focus includes critical care, pain and airway management, transesophageal echocardiography and pediatric and adult anesthesia care, particularly critical care and anesthesia for vascular, thoracic, transplant and trauma patients. Hanowell’s scholarly work focuses on the pharmacology and physiology of anesthetized and critically ill patients.

He received his MD (1977 AOA) from George Washington University. He trained in anesthesiology at Oregon Health Sciences University. He was a professor at the University of California-Davis in the departments of anesthesiology and medicine prior to joining Stanford medical center as a staff physician in July 2002. Hanowell is board-certified in anesthesiology, internal medicine, critical care, pain management and transesophageal echocardiography.

Stuart Kim, PhD, was promoted to professor of developmental biology. His research focuses on the organ development in C. elegans at the cellular and molecular level. Kim was the first to assemble the complete set of genes on microarrays and to study their regulation at the whole organism level. In 2002 he won an Ellison Senior Scholar Award in Aging for "Genomic approaches to studying aging in C. elegans." He was chosen to organize the 2003 International C. Elegans meeting in Madison, Wis., and the 2003 Keystone symposium on functional genomics in Santa Fe, N.M. He is a member of the NIH Cell Biology and Physiology Study section.

Kim received his PhD in molecular biology in 1984 from CalTech and completed a postdoctoral fellowship in 1989 at MIT. He was appointed assistant professor in the Department of Developmental Biology at Stanford in 1989 and was promoted to associate professor, with tenure, in 1996. In 1998 he received an appointment to the Department of Genetics as well.

David Kingsley, PhD, was promoted to professor of developmental biology. He is a Howard Hughes Medical Institute associate investigator. His research focuses on the developmental biology of the vertebrate skeleton. His laboratory has isolated several mouse genes that control bone and joint formation during embryogenesis, repair of bone fractures in adults, and susceptibility to arthritis. He has also pioneered the study of how new traits appear during vertebrate evolution, using the three-spine stickleback, a small teleost fish that has undergone recent and dramatic evolutionary changes. Kingsley has built a genome-wide linkage map with crosses between different forms to analyze mutations responsible for skeletal modifications. He is the recipient of a MERIT award from NIAMD for his work on bone morphogenetic proteins.

He received his PhD (biology) from MIT in 1986. He completed his postdoctoral training at MIT and the NCI-Frederick Cancer Research and Development Center. He came to Stanford as an assistant professor in 1991 and was promoted to associate professor, with tenure, in 1998.

Amy Ladd, MD, was promoted to professor of orthopedic surgery. Her current scholarly work focuses on two areas: research on bone graft substitutes and the development of innovative technology in education. Ladd produced the acclaimed Fractures of the Distal Radius: A Visual Approach, a CD-ROM published by the American Society for Surgery of the Hand. Her e-book on Paget’s disease, using the radiograph collection of Henry Jones, MD, won an award at the American Academy of Orthopaedic Surgeons annual meeting in 2003.

Ladd received her MD in 1984 from SUNY Upstate Medical Center, Syracuse, N.Y. Her postdoctoral training included a surgical internship at the Swedish Hospital in Seattle, a year in surgery at the University of Washington and an orthopedics residency at the University of Rochester. She was a hand surgery fellow at Harvard. She joined Stanford in 1990 and received a faculty appointment in 1991. She treats adult and pediatric patients and also works at the Palo Alto VA spinal cord unit.

Lawrence Recht, MD, was appointed professor of neurology and neurological sciences and, by courtesy, of neurosurgery. Recht is an established investigator and clinician in neurology, specifically in the area of brain cancer. His work includes clinical studies in neuro-oncology and basic research on neural stem cells and glioma. He has shown that endogenous stem-like cells are likely to be the first intermediates in glioma formation, using a model of rodent neuro-oncogenesis. He is currently continuing to link the brain’s proliferative zone, specifically the subventricular zone, to this process.

Recht obtained his medical degree from Columbia University in 1977. He trained in internal medicine at the University of Minnesota and in neurology at the Neurological Institute of New York. He received his neuro-oncology training at Memorial Sloan-Kettering Cancer Center. He joins Stanford from the University of Massachusetts Medical School, Worcestor, where he was a professor of neurology and surgery (neurosurgery).